I am so glad that I found this site. I was feeling very alone in this situation, but now I can see that there are others who are sharing my boat!
My husband and I have been trying to conceive for over a year now. I have never had regular cycles so I thought that we might need help. I was diagnosed with PCOS and prescribed Clomid. I took my first cycle of Clomid in March. On day 22, my progesterone level was low and I was told that I didn't ovulate. Imagine our surprise and immense joy when two weeks later, I had a positive HPT! My Ob was a little less hopeful, given that my progesterone level on day 22 was VERY low (1.4) so she sent me to have my progesterone level checked. It came back at 6.9 so I am starting progesterone suppositories today. From everything that I've read on the internet, this does not bode well for me to carry this pregnancy to term.
I also have Multiple Sclerosis. I read that people with autoimmune diseases can create antibodies to their own hormones, including progesterone, causing low levels.
Please, please, please tell me that somebody out there has had success with this treatment. Does anybody else have an autoimmune disease and success with progesterone supplements??? It must be successful sometimes or else they would stop prescribing it, right?